Journal of Health And Care
Volume 24, Issue 4 (winter 2023)
JHC 2023, 24(4): 331-341 |
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Ethics code: IR.SBMU.RETECH.REC.1398.398
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Heydari M, Keshavarzynejad M. Effect of Hydro-Alcoholic Extract of Capsella Bursa Pastoris on Postpartum Pain and Volume of Bleeding, a Randomized Clinical Trial. JHC 2023; 24 (4) :331-341
URL: http://hcjournal.arums.ac.ir/article-1-1381-en.html
URL: http://hcjournal.arums.ac.ir/article-1-1381-en.html
Department of Midwifery, Faculty of Medical Sciences, Islamic Azad University, Semnan, Iran
Abstract: (718 Views)
Background & aim: Postpartum pain or painful uterine contractions are one of the most common postpartum problems. This pain is affected by various factors and has maternal and neonatal adverse consequences. Nowadays, herbal and traditional remedies have been considered for management of this pain. The aim of this study was to evaluate the effect of hydroalcoholic extract of priest sachet Capsella bursa-pastoris on postpartum pain and volume of bleeding in women referring to Damghan Hospital affiliated to Semnan University of Medical Science.
Method: In this clinical trial, 110 mothers with vaginal delivery were enrolled. Inclusion criteria were postpartum pain criteria of four and more. Patients were randomly assigned into two groups, the first group received hydroalcoholic extract of Capsella bursa-pastoris and the other received placebo. Visual scale of pain was used to assess postpartum pain. Data were analyzed by SPSS-20 software using independent t-test, Mann-Whitney, Chi-square and analysis of variance with repeated measures and linear regression at significance level less than 0.05.
Results: The mean age was 29.13±6.6 years. The two groups were matched in terms of age and other factors including cultural and economic status, parity, delivery, and abortion, history of stillbirth and curettage, anthropometric indices, administration of oxytocin during labor, labor conditions and neonatal factors. There was no significant difference between the two groups in receiving of analgesics. Analysis of variance showed that time had a significant effect on pain severity, however, pain intensity at different times in the intervention group was significantly lower than control group (p=0.026).
Conclusion: Despite the effect of time on decreasing of postpartum pain, the severity of pain at different times in the intervention group was significantly lower than control group and recommended for postpartum pain.
Method: In this clinical trial, 110 mothers with vaginal delivery were enrolled. Inclusion criteria were postpartum pain criteria of four and more. Patients were randomly assigned into two groups, the first group received hydroalcoholic extract of Capsella bursa-pastoris and the other received placebo. Visual scale of pain was used to assess postpartum pain. Data were analyzed by SPSS-20 software using independent t-test, Mann-Whitney, Chi-square and analysis of variance with repeated measures and linear regression at significance level less than 0.05.
Results: The mean age was 29.13±6.6 years. The two groups were matched in terms of age and other factors including cultural and economic status, parity, delivery, and abortion, history of stillbirth and curettage, anthropometric indices, administration of oxytocin during labor, labor conditions and neonatal factors. There was no significant difference between the two groups in receiving of analgesics. Analysis of variance showed that time had a significant effect on pain severity, however, pain intensity at different times in the intervention group was significantly lower than control group (p=0.026).
Conclusion: Despite the effect of time on decreasing of postpartum pain, the severity of pain at different times in the intervention group was significantly lower than control group and recommended for postpartum pain.
Type of Study: randomized clinical trial |
Subject:
Midwifery
Received: 2022/08/3 | Accepted: 2023/02/5 | Published: 2023/03/1
Received: 2022/08/3 | Accepted: 2023/02/5 | Published: 2023/03/1
References
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8. Karimi A, Majlesi M, Rafieian-Kopaei M. Herbal versus synthetic drugs; beliefs and facts. Journal of Nephropharmacology. 2015;4(1):27-30.
9. Fang YC, Huang HC, Chen HH, Juan HF. TCMGeneDIT: a database for associated traditional Chinese medicine, gene and disease information using text mining. BMC Complementary and Alternative Medicine. 2008;8:58. [DOI:10.1186/1472-6882-8-58] [PMID] []
10. Shadipour M, Simbar M, Salamzadeh J, Nasire N. A comparative study on the effects of Menstrogol and Mefenamic acid on postpartum after-pain. Iranian South Medical Journal. 2014;16(6):401-409 [Persian[.
11. Chananeh M JAP, Dolatian M, Mojab F, Nasiri M. Effects of the combination of Nigella Sativa and Mefenamic Acid and Mefenamic Acid alone on the severity of postpartum pain in multiparous women: a double-blind clinical trial. Iranian Journal of Obstetrics, Gynecology and Infertility. 2018;21(4):62-71 [Persian].
12. Ghalandari S, Kariman N, Sheikhan Z, Mojab F, Mirzaei M, Shahrahmani H. Effect of Hydroalcoholic Extract of Capsella Bursa Pastoris on early postpartum hemorrhage: a clinical trial study. Journal of Alternative and Complementary Medicine. 2017;23(10):794-99. [DOI:10.1089/acm.2017.0095] [PMID]
13. Grosso C, Vinholes J, Silva LR, Pinho PGd, Gonçalves RF, Valentão P, et al. Chemical composition and biological screening of Capsella Bursa-Pastoris. Revista Brasileira de Farmacognosia. 2011;21(4):635-43. [DOI:10.1590/S0102-695X2011005000107]
14. Golabi S. Hassanpour Ezati M, Rohampour K. Effect of Aqueous Extracts of Sun-Dew (Drosera spatulata) on the firing rate of PGi nucleus neurons after formalin-induced pain in rats. Journal of Physiology and Pharmacology. 2010;14(3):282-87 [Persian].
15. Alghadir AH, Anwer S, Iqbal A, Iqbal ZA. Test-retest reliability, validity, and minimum detectable change of visual analog, numerical rating, and verbal rating scales for measurement of osteoarthritic knee pain. Journal of Pain Research. 2018;11:851-56. [DOI:10.2147/JPR.S158847] [PMID] []
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18. Hosseini M, Zakeri S, Khoshdast S, Yousefian FT, Rastegar M, Vafaee F, et al. The effects of Nigella Sativa Hydro-Alcoholic Extract and Thymoquinone on lipopolysaccharide-induced depression like behavior in rats. Journal of Pharmacy & Bioallied Sciences. 2012;4(3):19-25. [DOI:10.4103/0975-7406.99052] [PMID] []
19. Ozgoli G, Khodadadie A, Sheikhan Z, Jambarsang S, Mojab F, Taleb S. Comparison of efficacy between herbal Capsule of Anise and Mefenamic Acid on after-pain. Journal of Medicinal Plants. 2017;2(62):38-45 [Persian].
20. Namazi M, Amir Ali Akbari S, Mojab F, Talebi A, Alavi Majd H, Jannesari S. Aromatherapy with Citrus Aurantium oil and anxiety during the first stage of labor. Iranian Red Crescent Medical Journal. 2014;16(6):e18371. [DOI:10.5812/ircmj.18371] [PMID] []
21. Dashe JS, Bloom SL, Spong CY, Hoffman BL. Williams obstetrics. McGraw Hill Professional; 2018.
22. Jangsten E, Bergh I, Mattsson LA, Hellstrom AL, Berg M. Afterpains: A comparison between active and expectant management of the third stage of labor. Birth. 2011;38(4):294-301. [DOI:10.1111/j.1523-536X.2011.00487.x] [PMID]
23. Rafiei M, Behnamfar F, Abdekhoda M, Mosavi G. Evaluation of the effect of epidural anesthesia with marcaine and fentanyl on labor course and neonatal apgar scores. Koomesh. 2006;7(1):35-40 [Persian].
24. Deussen AR, Ashwood P, Martis R. Analgesia for relief of pain due to uterine cramping/involution after birth. The Cochrane database of systematic reviews. 2011(5):Cd004908. [DOI:10.1002/14651858.CD004908.pub2] [PMID]
25. Fahey JO. Best practices in management of postpartum pain. The Journal of Perinatal & Neonatal Nursing. 2017;31(2):126-36. [DOI:10.1097/JPN.0000000000000241] [PMID]
26. Obstetricians ACOG. ACOG Committee Opinion No. 742: Postpartum pain management. Obstetrics and Gynecology. 2018;132(1):e35-e43. [DOI:10.1097/AOG.0000000000002683]
27. Karimi A, Majlesi M, Rafieian-Kopaei M. Herbal versus synthetic drugs; beliefs and facts. Journal of Nephropharmacology. 2015;4(1):27-30.
28. Fang YC, Huang HC, Chen HH, Juan HF. TCMGeneDIT: a database for associated traditional Chinese medicine, gene and disease information using text mining. BMC Complementary and Alternative Medicine. 2008;8:58. [DOI:10.1186/1472-6882-8-58] [PMID] []
29. Shadipour M, Simbar M, Salamzadeh J, Nasire N. A comparative study on the effects of Menstrogol and Mefenamic acid on postpartum after-pain. Iranian South Medical Journal. 2014;16(6):401-409 [Persian[.
30. Chananeh M JAP, Dolatian M, Mojab F, Nasiri M. Effects of the combination of Nigella Sativa and Mefenamic Acid and Mefenamic Acid alone on the severity of postpartum pain in multiparous women: a double-blind clinical trial. Iranian Journal of Obstetrics, Gynecology and Infertility. 2018;21(4):62-71 [Persian].
31. Ghalandari S, Kariman N, Sheikhan Z, Mojab F, Mirzaei M, Shahrahmani H. Effect of Hydroalcoholic Extract of Capsella Bursa Pastoris on early postpartum hemorrhage: a clinical trial study. Journal of Alternative and Complementary Medicine. 2017;23(10):794-99. [DOI:10.1089/acm.2017.0095] [PMID]
32. Grosso C, Vinholes J, Silva LR, Pinho PGd, Gonçalves RF, Valentão P, et al. Chemical composition and biological screening of Capsella Bursa-Pastoris. Revista Brasileira de Farmacognosia. 2011;21(4):635-43. [DOI:10.1590/S0102-695X2011005000107]
33. Golabi S. Hassanpour Ezati M, Rohampour K. Effect of Aqueous Extracts of Sun-Dew (Drosera spatulata) on the firing rate of PGi nucleus neurons after formalin-induced pain in rats. Journal of Physiology and Pharmacology. 2010;14(3):282-87 [Persian].
34. Alghadir AH, Anwer S, Iqbal A, Iqbal ZA. Test-retest reliability, validity, and minimum detectable change of visual analog, numerical rating, and verbal rating scales for measurement of osteoarthritic knee pain. Journal of Pain Research. 2018;11:851-56. [DOI:10.2147/JPR.S158847] [PMID] []
35. Boonstra AM, Schiphorst Preuper HR, Reneman MF, Posthumus JB, Stewart RE. Reliability and validity of the visual analogue scale for disability in patients with chronic musculoskeletal pain. International Journal of Rehabilitation Research. 2008;31(2):165-69.
https://doi.org/10.1097/MRR.0b013e3282fc0fdf [DOI:10.1097/MRR.0b013e3282fc0f93]
36. Parsa L, Ozgoli G. A systematic on the medicinal plants used in the treatment of postpartum pain in Iran. Iranian Journal of Obstetrics, Gynecology and Infertility. 2017;20(5):84-96 [Persian].
37. Hosseini M, Zakeri S, Khoshdast S, Yousefian FT, Rastegar M, Vafaee F, et al. The effects of Nigella Sativa Hydro-Alcoholic Extract and Thymoquinone on lipopolysaccharide-induced depression like behavior in rats. Journal of Pharmacy & Bioallied Sciences. 2012;4(3):19-25. [DOI:10.4103/0975-7406.99052] [PMID] []
38. Ozgoli G, Khodadadie A, Sheikhan Z, Jambarsang S, Mojab F, Taleb S. Comparison of efficacy between herbal Capsule of Anise and Mefenamic Acid on after-pain. Journal of Medicinal Plants. 2017;2(62):38-45 [Persian].
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